If you have chronic obstructive pulmonary disease (COPD) or asthma, living with coughing, wheezing and shortness of breath can make it hard to do the things you want to do.
A combination inhaler known as Trelegy Ellipta may help manage these chronic respiratory conditions. It combines three powerful medications into one inhaler you use once a day to help control symptoms and prevent flare-ups.
This combination inhaler includes:
- Fluticasone: This corticosteroid helps lower inflammation in the airways to help reduce swelling and irritation and make it easier to breathe.
- Umeclidinium: This long-acting medication blocks receptors in the airways that lead to muscle contraction and mucus production. It helps relax and widen the airways.
- Vilanterol: This long-acting beta-agonist (LABA) helps relax the muscles around the airways, so it’s easier for air to flow in and out of the lungs.
With this combination, you can address different treatment needs in a single device. “This makes Trelegy Ellipta a comprehensive treatment option for COPD and asthma that addresses inflammation, bronchoconstriction and airway tightening all in one inhaler,” said Paul Thompson, a pharmacist with Banner Pharmacy Services. It can make asthma and COPD flareups less frequent and less severe, so your daily routine isn’t interrupted and you don’t need as many emergency medical interventions.
Using it once a day is convenient — you don’t have to remember many medications and dosages. It can also make it easier to follow your treatment plan. “Many people find that Trelegy Ellipta simplifies their regimen. Instead of taking multiple inhalers, they can now use a single inhaler once a day,” Dr. Thompson said.
How to use Trelegy Ellipta
You need to use Trelegy Ellipta correctly for it to work properly. Here’s a step-by-step guide:
- Remove the inhaler from its foil cover when you are ready to use it.
- Hold the inhaler upright and slide the cover down until you hear a click, which releases a dose of medication.
- Breathe out gently but fully to empty your lungs.
- Place the mouthpiece between your lips, ensuring a tight seal. Breathe in quickly and deeply through your mouth to inhale the full dose.
- After inhaling, hold your breath for about 10 seconds so the medication can reach deep into your lungs.
- Close the inhaler cover to help keep it dry and to prepare it for the next use.
- Rinse your mouth after using the inhaler. “That can help prevent oral thrush, a common side effect of inhaled corticosteroids,” Dr. Thompson said.
Use the inhaler at the same time each day. Being consistent helps control your symptoms better. “Adhering to the once-daily dosing regimen and ensuring you’re inhaling the medication properly will maximize its effectiveness,” Dr. Thompson said. Follow your health care provider’s instructions on the exact dosage.
Store the inhaler in a cool, dry place. Don’t expose it to moisture or extreme temperatures. Keep the inhaler in its original packaging until you are ready to use it. Wipe the mouthpiece regularly with a clean, dry cloth to prevent any medication buildup. Do not wash it with water.
Possible side effects
“Many people use this inhaler without having any major problems,” Dr. Thompson said. However, it’s important to be aware of possible side effects and know what to do if they occur.
Common side effects:
- Sore throat: This is generally mild and usually clears up if you drink plenty of fluids.
- Hoarseness or cough: This can occur due to the corticosteroid in the medication.
- Headaches: They are usually mild and temporary.
- Upper respiratory infections: These usually clear up without complications.
Serious side effects:
- Worsening breathing: If you notice your breathing becomes more difficult or your symptoms get worse, you may be having a serious reaction. Seek medical attention right away.
- Increased heart rate: If you notice a faster heartbeat or feel palpitations, consult your health care provider.
Tell your health care provider about any side effects, especially if they are severe or persistent. They can tell you how to manage them or figure out if you need different treatment. Follow up regularly to see how your treatment is working and to monitor any side effects.
For serious side effects such as trouble breathing or other severe symptoms, it’s important to get help right away.
Precautions and warnings for Trelegy Ellipta
Some people may need to avoid taking Trelegy Ellipta or be cautious with it.
- You should not use Trelegy Ellipta if you’re allergic to fluticasone, umeclidinium, vilanterol or any other ingredients in it.
- If you have recently had a heart attack or have severe heart disease, you may need to avoid Trelegy Ellipta because it can affect your heart rate and blood pressure.
- If your asthma is not well-controlled with other treatments, Trelegy Ellipta might not be the best option until your asthma is better managed.
- Let your health care provider know about all other respiratory medications you are taking. Combining them with Trelegy Ellipta may change how effective it is or increase the risk of side effects.
- CYP3A4 Inhibitors, such as ketoconazole and certain HIV medications, can affect the way you metabolize vilanterol (a component of Trelegy Ellipta). Your provider may need to adjust your treatment plan if you are taking these drugs.
- Beta-blockers might affect how well Trelegy Ellipta works and/or worsen side effects. Discuss any other medications you take with your provider.
Lifestyle tips for managing COPD and asthma
Along with using Trelegy Ellipta, lifestyle changes can improve the way you manage COPD and asthma. Here are some tips:
- Identify and avoid triggers: Common triggers include pollen, dust mites, pet dander, smoke, strong odors and cold air. Take steps to avoid or minimize exposure.
- Create a healthy environment: Keep your living areas clean and free of allergens. Use air purifiers, regularly clean surfaces and make sure you have good ventilation.
- Get regular exercise: Exercise can strengthen your respiratory muscles, improve endurance and help manage weight. Talk to your provider before starting a new exercise program to make sure it is safe for you.
- Participate in a pulmonary rehabilitation program: These programs often include education on managing your condition, breathing exercises and physical training. They can help improve your lung function and quality of life.
- Stay up-to-date on vaccines: Get your yearly flu vaccine. If your provider recommends it, get the pneumonia vaccine.
- Choose a balanced diet: A nutritious diet supports your health and can help manage weight, which is important for respiratory health. Center your diet around fruits, vegetables, whole grains and lean proteins.
- Drink plenty of water: Staying hydrated helps keep mucus thin and easier to clear, reducing the risk of blockages and infections in your airway.
The bottom line
Trelegy Ellipta is an inhaled medication that combines three active ingredients (fluticasone, umeclidinium and vilanterol) to treat COPD and asthma. You take it once a day, so it can be a convenient alternative to taking multiple medications daily. But it may cause side effects and it’s not the right choice for everyone.
Your health care provider or an expert at Banner Health can review your symptoms and health history and help you decide if Trelegy Ellipta might be a good option for you.
Other useful articles
- Protect Your Lungs: Asthma Relief in Dust Storms and Wildfires
- Tips for Preventing and Treating Asthma Attacks When You’re Traveling
- 5 Common Myths About COPD (Hint: There’s Help)
The content in this article is for informational use only. Always discuss any medication with your health care provider or pharmacist before taking it. Also, refer to the medication package insert supplied by the pharmaceutical manufacturer with your prescription.
